FDA Approvals:

• 1961 Vinblastine: a drug that binds to tubulin. Derived from the ornamental shrub, vinca rosea.

• 1962 5-FU

• 1963 Vincristine: a sister drug to Vinblastine.

• 1964 Melphalan (L-PAM) approved for marketing.

1966 NCI standardizes testing of cancer-causing chemicals.

1969 R. Heubner & G. Todaro propose the oncogene hypothesis.

Decorative Image: Scientist in lab.