1978
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First human testing of a biological therapy (alpha-interferon).
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Tamoxifen approved by FDA for marketing as a treatment drug.
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FDA approves cisplatin, a powerful anticancer drug.
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Metastatic cells shown to arise from pre-existing subpopulations in primary tumors.
1979
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P53 discovered, most frequently mutated gene in human cancer.
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Modified radical mastectomy replaces radical mastectomy for breast cancer.
