1981 Introduction of first human viral vaccine that can prevent cancer (hepatitis B virus vaccine for liver cancer).

1984 The human p53 tumor suppressor gene cloned.

1985 Lumpectomy plus radiation found equivalent to mastectomy for breast cancer.

Adjuvant chemotherapy:

• 1988 Proven to increase disease-free survival in early breast cancer

• 1989 Proven to increase survival in colon cancer

Decorative Image: Patient