Snorri S. Thorgeirsson, M.D., Ph.D.

Dr. Thorgeirsson joined the NCI in 1976, and has been the Chief of the Laboratory of Experimental Carcinogenesis since 1981. He obtained his M.D. degree from the University of Iceland; he studied biochemistry and pharmacology with Sir Colin Dollery and Dr. Donald S. Davies at the Royal Postgraduate Medical School in London, England and obtained his Ph.D. from the University of London.

Research Interests: application of transgenic mouse models as paradigms for human diseases and stem cell biology.

Library of Medicine On-Line Publication List (with abstracts)

Other Recent Publications

Grisham, J. W. and Thorgeirsson, S. S. Liver stem cells. In: Potten, C. S. (Ed.): Stem Cells, Academic Press, London, 1997, 233-82.
Thorgeirsson, S. S. Stem cells and hepatocarcinogenesis. In: Jirtle, R. L. (ed.). Liver Regeneration and Carcinogenesis: Cellular and Molecular Mechanisms, Academic Press, New York, 1995, 99-112.
Schrenk, D., Gant, T. W., Silverman, J. A., and Thorgeirsson, S. S. Induction of multidrug resistance gene products in cholesasis. In Keppler, D. and Jungermann, K. (eds.): Transport in the Liver, Proceedings of the Falk Symposium #74, Kluwer Academic Publishers, Lancaster, UK, 1994, 243-52.
Muller, M., Mittenbuhler, K., Mayer, R., Wallstab, A., Silverman, J. A., Thorgeirsson, S. S., and Keppler, D. ATP-dependent transport of amphiphilic cations across the canalicular membrane mediated by P-glycoprotein. In: Keppler, D. (Ed.), Transport in the Liver, Proceedings of Falk Symposium #74, Kluwer Academic Publishers, Lancaster, UK, 1994, 156-65.
Thorgeirsson, S. S., Evarts, R. P., Fujio, K., and Hu, Z. Cellular biology of the rat hepatic stem cell compartment. In: Skouteris, G. G. (Ed.): NATO ASI Series Volume H88, Liver Carcinogenesis: The Molecular Pathways, Springer-Verlag, Berlin/Heidelberg, 1994, 129-45.
Adamson, R. H., Thorgeirsson, U. P., Snyderwine, E. G., Thorgeirsson, S. S., Takayama, S., and Sugimura, T. Interspecies studies on heterocyclic amines and the need for mechanistic understanding. In Somogyi, A., Appel, K. E., Katenkamp, A. (Eds.): Proceedings of the Symposium on Chemical Carcinogenesis: The Relevance of Mechanistic Understanding in Toxicological Evaluation. Munich, BGA-Schrriften, 1992, 43-7.
Thorgeirsson, S. S. and Evarts, R. P. Growth and differentiation of stem cells in adult rat liver. In Sirica, A. E. (Ed.): The Role of Cell Types in Hepatocarcinogenesis, CRC Press, 1992, 110-20.
Thorgeirsson, S. S., Huggett, A. C., and Bisgaard, H. C. Phenotypic characteristics and neoplastic transformation of primitive epithelial cells derived from rat liver and pancreas. In Clement, B. and Guillouzo, A. (Eds.): Cellular and Molecular Aspects of Cirrhosis, Colloque INSERM, Vol. 216, John Libbey Eurotext, 287-98, 1992.
Last revised 3/27/97.
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