ANNUAL BIBLIOGRAPHY

(2012-PRESENT)

 

Molecular Genetics & Carcinogenesis Section

 

Heegaard, N. H., Schetter, A. J., Welsh, J. A., Yoneda, M., Bowman, E. D. and Harris, C. C.: Circulating micro-RNA expression profiles in early stage nonsmall cell lung cancer. Int. J. Cancer, 130: 1378-1386, 2012.

 

Kohno, T., Ichikawa, H., Totoki, Y., Yasuda, K., Hiramoto, M., Nammo, T., Sakamoto, H., Tsuta, K., Furuta, K., Shimada, Y., Iwakawa, R., Ogiwara, H., Oike, T., Enari, M., Schetter, A. J., Okayama, H., Haugen, A., Skaug, V., Chiku, S., Yamanaka, I., Arai, Y., Watanabe, S., Sekine, I., Ogawa, S., Harris, C. C., Tsuda, H., Yoshida, T., Yokota, J., and Shibata, T.: KIF5B-RET fusions in lung adenocarcinoma. Nature Medicine, 18: 375-377, 2012.

 

Zanetti, K. A., Haznadar, M., Welsh, J. A., Robles, A. I., Ryan, B. M., McClary, A. C., Bowman, E. D., Goodman, J. E., Bernig, T., Chanock, S. J. and Harris, C. C.: 3ÕUTR and functional secretor haplotypes in mannose-binding lectin 2 are associated with increased colon cancer risk in African-Americans. Cancer Res., 72: 1467-77, 2012.

 

CotŽ, M. L., Liu, M., Bonassi, S., Neri, M., Schwartz, A. G., Christiani, D. C., Spitz, M. R., Muscat, J. E., Rennert, G., Aben, K. K., Andrew, A. S., Bencko, V., Bickebšller, H., Boffetta, P., Brennan, P., Brenner, H., Duell, E. J., Fabianova, E., Field, J. K., Foretova, L., Friis, S., Harris, C. C., Holcatova, I., Hong, Y. C., Isla, D., Janout, V., Kiemeney, L. A., Kiyohara, C., Lan, Q., Lazarus, P., Lissowska, J., Le Marchand, L., Mates, D., Matsuo, K., Mayordomo, J. I., McLaughlin, J. R., Morgenstern, H., MŸeller, H., Orlow, I., Park, B. J., Pinchev, M., Raji, O.Y., Rennert, H. S., Rudnai, P., Seow, A., Stucker, I., Szeszenia-Dabrowska, N., Dawn Teare, M., Tj¿nnelan, A., Ugolini, D., van der Heijden, H. F., Wichmann, E., Wiencke, J. K., Woll, P. J., Yang, P., Zaridze, D., Zhang, Z. F., Etzel, C. J. and Hung, R. J.: Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium. Eur J Cancer, 48: 1957-1968, 2012.

 

Taga, M., Mechanic, L. E., Hagiwara, N., Vahakangas, K. H., Bennett, W. P., Alavanja, M. C., Welsh, J. A., Khan, M. A., Lee, A., Diasio, R., Edell, E., Bungum, A., Jang, J. S., Yang, P., Jen, J. and Harris, C. C.: EGFR somatic mutations in lung tumors: radon exposure and passive smoking in former- and never-smoking U.S. women. Cancer Epidemiol. Biomarkers Prev., 21: 988-992, 2012.

 

Jacobs, K. B., Yeager, M., Zhou, W., Wacholder, S., Wang, Z., Rodriguez-Santiago, B., Hutchinson, A., Deng, X., Liu, C., Horner, M. J., Cullen, M., Epstein, C. G., Burdett, L., Dean, M. C., Chatterjee, N., Sampson, J., Chung, C. C., Kovaks, J., Gapstur, S. M., Stevens, V. L., Teras, L. T., Gaudet, M. M., Albanes, D., Weinstein, S. J., Virtamo, J., Taylor, P. R., Freedman, N. D., Abnet, C. C., Goldstein, A. M., Hu, N., Yu, K., Yuan, J. M., Liao, L., Ding, T., Qiao, Y. L., Gao, Y. T., Koh, W. P., Xiang, Y. B., Tang, Z. Z., Fan, J. H., Aldrich, M. C., Amos, C., Blot, W. J., Bock, C. H., Gillanders, E. M., Harris, C. C., et al.,  Chanock, S. J.: Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genetics, 44: 651-658, 2012.

 

Schetter, A. J. and Harris, C. C.: Tumor Suppressor p53 (TP53) at the crossroads of the exposome and the cancer genome, Proc Natl Acad Sci USA, 109: 7955-7956, 2012.

 

Shaked, H., Hofseth, L. J., Chumanevich, A., Chumanevich, A. A., Wang, J., Wang, Y., Taniguchi, K., Guma, M., Shenouda, S., Clevers, H., Harris, C. C. and Karin, M.: Chronic epithelial NF-ΚB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation. Proc Natl Acad Sci USA, 109: 14007-14012, 2012.

 

Jang, J. S., Jeon, H. S., Sun, Z., Aubry, M. C., Tang, H., Park, C. H., Pakhshan, F., Shultz, D. A., Kolbert, C. P., Lupu, R., Park, J. Y., Harris, C. C., Yang, P. and Jin, J.: Increased miR-708 expression in NSCLC and its association with poor survival in lung adenocarcinoma from never smokers. Clin.Cancer Res., 18: 3658-3667, 2012.

 

Ryan, B. M., McClary, A. C., Valeri, N., Robinson, D., Paone, A., Bowman, E. D., Robles, A. I., Croce, C. and Harris, C. C.: rs4919510 in has-mir-608 is associated with outcome but not risk of colorectal cancer. PLos One, 7: e36306.

 

Ryan, B. M., Calhoun, K. M., Pine, S. R., Bowman, E. D., Robles, A. I., Ambs, S. and Harris, C. C.: MDM2 SNP285 does not antagonize the effect of SNP309 in lung cancer. Int J Cancer, 131: 2710-2716, 2012.

 

Okayama, H., Saito, M., Oue, N., Weiss, J. M., Stauffer, J., Takenoshita, S., Wiltrout, R. H., Hussain, S. P. and Harris, C. C.: NOS2 enhances KRAS-induced lung carcinogenesis, inflammation and microRNA-21 expression. Int J Cancer. 132: 9-18, 2012.

 

Ryan, B. M., Robles, A. I. and Harris, C. C.: KRAS-LCS6 genotype as a prognostic marker in early-stage CRC--letter. Clin Cancer Res., 18: 3487-3488, 2012.

 

Tang, Y., Horikawa, I., Ajiro, M., Robles, A. I., Fujita, K., Mondal, A. M., Stauffer, J. K., Zheng, Z. M. and Harris, C. C.: Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence. Oncogene. 2012 July 9 [Epub ahead of print].

 

Gaedcke, J., Grade, M., Camps, J., Sokide, R., Kaczkowski, B., Schetter, A. J., Difilippantoio, M. J., Harris, C. C., Ghadimi, B. M., Moller, S., Beissbarth, T., Ried, T. and Litman, T.: The rectal cancer microRNAome – microRNA expression in rectal cancer and matched normal mucosa. Clin Cancer Res., 18: 4919-4930, 2012.

 

Sohn, J. J., Schetter, A. J., Yfantis, H. G., Ridnour, L. A., Khan, M. A., Robles, A. I., Hussain, S. P., Goto, A., Bowman, E. D., Hofseth, L. J., Bartkova, J., Bartek, J., Wogan, G. N., Wink, D. A. and Harris, C. C.: Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel disease. PLoS One, 7: e44156, 2012.

 

Weng, M. T., Lee, J. H., Wei, S. C., Li, Q., Shahamatdar, S., Hsu, D., Schetter, A. J., Swatkoski, S., Mannan, P., Garfield, S., Gucek, M., Kim, M. K. H., Annunziata, C. M., Creighton, C. J., Emanuele, M. J., Harris, C. C., Sheu, J. C., Giaccone, G. and Luo, J.: The evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells. Proc. Natl. Acad. Science, 109: E3659-67, 2012.

 

Zhao, Y., Schetter, A. J., Yang, G. B., Nguyen, G., Mathe, E. A., Li, P., Cai, H., Yu, L., Liu, F., Hang, D., Yang, H., Wang, X. W., Ke, Y. and Harris, C. C.: Inflammatory and microRNA gene expression as prognostic marker for overall survival in esophageal squamous cell carcinoma. Int J Cancer, 2012 Nov 23 [Epub ahead in print].

 

Cui, X., Witalison, E. E., Chumanevich, A. P., Chumanevich, A. A., Poudyal, D., Subramanian, V., Schetter, A. J., Harris, C. C., Thompson, P. R. and Hofseth, L. J.: The induction of microRNA-16 in colon cancer cells by protein arginine deiminase inhibition causes a p53-dependent cell cycle arrest. PLoS One, 8: e53791, 2013.

 

Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, V. A., Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. and Hickson, I. D.: A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells. Chem Biol., 20: 55-62, 2013.

 

Okayama, H., Saito, M., Oue, N., Weiss, J. M., Stauffer, J., Takenoshita, S., Wiltrout, R. H., Hussain, S. P. and Harris, C. C.: NOS2 enhances KRAS-iduced lung carcinogenesis, inflammation and microRNA-21 expression. Int J. Cancer, 132: 9-18, 2013.

 

Liver Carcinogenesis Section

 

 

Roessler S, Long EL, Budhu A, Chen Y, Zhao X, Ji J, Walker R, Jia HJ, Ye QH, Qin LX, Tang ZY, He P, Hunter KW, Thorgeirsson SS, Meltzer PS, Wang XW. Integrative genomic identification of genes on 8p associated with hepatocellular carcinoma progression and patient survival. Gastroenterology 142: 957-66, 2012

 

Kim SM, Leem SH, Chu IS, Park YY, Kim SC, Kim SB, Park ES, Lim JY, Heo J, Kim YJ, Kim DG, Kaseb A, Park YN, Wang XW, Thorgeirsson SS, Lee JS. Sixty-Five gene-based risk score classifier predicts overall survival in hepatocellular carcinoma. Hepatology 55: 1443-52, 2012

 

Zhao F, Hoechst B, Gamrekelashvili J, Ormandy L, Voigtlander T, Wedemeyer H, Ylaya K, Wang XW, Hewitt SM, Manns MP, Korangy F, Greten TF. Human CCR4+CCR6+ TH17 cells suppress autologous CD8+ T cell responses. Journal of Immunology 188: 6055-62, 2012

 

Xue W, Kitzing TM, Roessler S, Zuber J, Krasnitz A, Schultz N, Revill K, Weismueller S, Rappaport A, Simon J, Zhang J, Luo W, Hicks J, Zender L, Wang XW, Powers S, Wigler M, Lowe SW. A cluster of cooperating tumor suppressor gene candidates in chromosomal deletions. Proc NatÕl Acad Sci USA 109: 8212-7, 2012

 

Oishi N, Kumar MR, Roessler S, Ji J, Forgues M, Budhu A, Zhao X, Andersen JB, Ye QH, Jia HL, Qin LX, Yamashita T, Woo HG, Kim YJ, Kaneko S, Tang ZY, Thorgeirsson SS, Wang XW. Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of mir-200c and EMT in intrahepatic cholangiocarcinoma. Hepatology 56: 1792-1803, 2012

 

Zhao Y, Schetter AJ, Yang GB, Nguyen G, Mathe EA, Li P, Cai H, Yu L, Liu F, Hang D, Yang H, Wang XW, Ke Y, Harris CC. Inflammatory and microRNA gene expression as prognostic marker for overall survival in esophageal squamous cell carcinoma. International Journal of Cancer 2013, In Press

 

Oikawa T, Kamiya A, Zeniya M, Chikada H, Hyuck AD, Yamazaki Y, Wauthier E, Tajiri H, Miller LD, Wang XW, Reid LM, Nakauchi H. SALL4 as an indicator of cancer stem cells in liver cancer. Hepatology 2013, In Press

 

Yamashita T, Honda M, Nakamoto Y, Baba M, Nio K, Hara Y, Zeng SS, Hayashi T, Kondo M, Takatori H, Yamashita T, Mizukoshi E, Ikeda H, Zen Y, Takamura H, Wang XW, Kaneko S. Natures of EpCAM+ and CD90+ Cancer Stem Cells in Human Hepatocellular Carcinoma. Hepatology 2013, In Press

 

Budhu A, Roessler S, Zhao X, Yu Z, Forgues M, Ji J, Karoly E, Qin LX, Ye QH, Jia HL, Fan J, Sun HC, Tang ZY, Wang XW. Integrated metabolite and gene expression profiles identify lipid biomarkers associated with progression of hepatocellular carcinoma and patient outcomes. Gastroenterology 2013, In Press

 

Feng M, Gao W, Wang R, Chen W, Man YG, Fig WD, Wang XW, Dimitrov DS, Ho M. Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma. Proc NatÕl Acad Sci USA 2013, In Press

 

Ji, J#, Yu L, Yu, Z, Forgues M, Uenishi K, Kubo S, Zhou J, Fan J, Tang ZY, Fu S, Zhu H, Jin JG4, Sun HC, Wang XW#. Development of a miR-26 Companion Diagnostic Test for Adjuvant Interferon-alpha Therapy in Hepatocellular Carcinoma. (#co-corresponding author) International Journal of Biological Sciences In Press

 

 

Molecular Epidemiology Section

 

Wang-Johanning, F., Rycaj, K., Plummer, J.B., Li, M., Yin, B., Frerich, K., Garza, J.G., Shen, J.J., Lin, K., Yan, P., Glynn, S.A., Dorsey, T.H., Hunt, K.K., Ambs, S., and Johanning, G.L. Immunotherapeutic potential of anti-human endogenous retrovirus-K envelope protein antibodies in targeting breast tumors. JNCI, 104: 189-210, 2012.

 

Hudson, R.S., Yi, M., Esposito, D., Watkins S.K., Hurwitz, A.A., Yfantis, H.G., Lee, D.H., Borin, J.F., Naslund, M.J., Alexander, R.B., Stephens, R.M., Croce, C.M., and Ambs, S. MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer. Nucleic Acids Res., 40: 3689-3703, 2012.

 

Zheng, Y., Ogundiran, T.O., Adebamowo, C., Nathanson, K.L., Domchek, S.M., Rebbeck, T.R., Simon, M.S., John, E.M., Hennis, A., Nemesure, B., Wu, S.Y., Leske, M.C., Ambs, S., Niu, Q., Zhang, J., Cox, N.J., Olopade, O.I., and Huo, D. Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry. Breast Cancer Res. Treat., 132: 341-345, 2012.

 

Hou, N., Zheng, Y., Gamazon, E.R., Ogundiran, T.O., Adebamowo, C., Nathanson, K.L., Domchek, S.M., Rebbeck, T.R., Simon, M.S., John, E.M., Hennis, A., Nemesure, B., Wu, S.-Y., Leske, C.M., Ambs, S., Niu, Q., Zhang, J., Pierce, B.L., Cox, N.J., Olopade, O.I.,  and Huo, D. Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry. Cancer Epidemiol. Biomarkers Prev., 21: 552-556, 2012.

 

Huo, D., Zheng, Y., Ogundiran, T.O., Adebamowo, C., Nathanson, K.L., Domchek, S.M., Rebbeck, T.R., Simon, M.S., John, E.M., Hennis, A., Nemesure, B., Wu, S.-Y., Leske, C.M., Ambs, S., Niu, Q., Zhang, J., Cox, N.J., and Olopade, O.I. Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry. Carcinogenesis, 33: 835-840, 2012.

 

Switzer, C.H., Cheng, R.Y., Ridnour, L.A., Murray, M.C., Tazzari, V., Sparatore, A., Del Soldato, P., Hines, H.B., Glynn, S.A., Ambs, S., and Wink, D.A. Dithiolethiones inhibit NF-kB activity via covalent modification in human estrogen receptor-negative breast cancer. Cancer Res., 72: 2394-2404, 2012.

 

Wang, S., Dorsey, T.H., Terunuma, A., Kittles, R.A., Ambs, S., and Kwabi-Addo, B. Relationship between tumor DNA methylation status and patient characteristics in African-American and European-American women with breast cancer. PLoS One 7: e37928, 2012.

 

Ryan, B.M., Calhoun, K.M., Pine, S.R., Bowman, E.D., Robles, A.I., Ambs, S., and Harris, C.C. MDM2 SNP285 does not antagonize the effect of SNP309 in lung cancer. Int. J. Cancer 131: 2710-2716, 2012.

 

Switzer, C.H., Glynn, S.A., Cheng, R.Y.-S., Ridnour, L.A., Green, J.E., Ambs, S., and Wink, D.A. S-Nitrosylation of EGFR and Src activates an oncogenic signaling network in human basal-like breast cancer. Mol. Cancer Res. 10: 1203-1215, 2012.

 

Ridnour, L.A., Barasch, K.M., Windhausen, A.N., Dorsey, T.M., Lizardo, M.M., Yfantis, H.G., Lee, D.H., Switzer, C.H., Glynn, S.A., Cheng, R.Y.S., Khanna, C., Ambs, S., and Wink, D.A. Nitric Oxide Synthase and Breast Cancer: Role of TIMP-1 in NO-mediated Akt Activation. PLoS One 7: e44081, 2012.

 

Hudson, R.S., Yi, M., Esposito, D., Glynn, S.A., Starks, A.M., Yang, Y., Schetter, A.J., Watkins, S.K., Hurwitz, A.A., Dorsey, T.H., Stephens, R.M., Croce, C.M., and Ambs, S. MicroRNA-106b-25 cluster expression is associated with early disease recurrence and targets caspase-7 and focal adhesion in human prostate cancer. Oncogene 2012 (Epub)

 

Ambs, S. Analysis of stromal gene expression for the identification of prognostic and predictive molecular markers in cancer therapy. Int. J. Cancer 131: 2213-2214, 2012.

 

Switzer, C.H., Cheng, R. Y.-S., Ridnour, L.A., Glynn, S.A., Ambs, S., and Wink, D.A. Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer. Breast Cancer Res., 14: R125, 2012.

 

Chen, F., Chen G.K., Stram, D.O., Millikan, R.C., Ambrosone, C.B., John E.M., Bernstein, L., Zheng, W., Palmer, J.R., et al. A genome-wide association study of breast cancer in women of African ancestry. Hum. Genet. 2012 (Epub)

 

Hudson, R.S., Yi, M., Volfovsky, N., Prueitt, R.L., Esposito, D., Volinia, S., Liu, C.-G., Stephens, R.M., Calin, G.A., Croce, C.M., and Ambs, S. Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer. (submitted)

 

Starks, A.M., Martin, D.N., Dorsey, T.H., Boersma, B.J., Wallace, T.A., and Ambs, S. Household income is associated with the p53 mutation frequency in breast tumors. (submitted)

 

Watkins, S.K., Stagliano, K.E.R., Weiss, J.M., Alexander, R.B., Borin, J.F., Naslund, M.J., Gilfillan, A.M., Ambs, S., and Hurwitz, A.A. Tumor-associated mast cells suppress anti-tumor immunity via IL-13 and TGF-β. (submitted)

 

Pancreatic Cancer Unit

 

Mathe, E., Nguyen, G., Funamizu, N., He, P., Moake, M., Croce, C.M and Hussain, S.P:

Inflammation regulates microRNA expression in cooperation with p53 and nitric oxide.  Int. J. Cancer, 131, 760-765, 2012.

 

Zhang G, Schetter A, He P, Funamizu N, Gaedcke J, Ghadimi BM, Ried T, Hassan R, Yffantis HG, Lee DH, Lacy C, Maitra A, Hanna N, Alexander HR, Hussain SP: DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma. PLoS One, 7 (2), e31507, 2012.

 

Okayama, H., Saito, M., Oue, N., Weiss, J.M., Stauffer, J., Takenoshita, S., Wiltrout, R.H., Hussain, S.P, Harris CC: NOS2 enhances KRAS-induced lung carcinogenesis, inflammation and microRNA-21 expression. Int. J. Cancer, May 23, Epub, 2012.

 

Funamizu N, Hu C, Lacy C, Schetter A, Zhang G, He P, Gaedcke J, Ghadimi BM, Ried T, Yffantis HG, Lee DH, Subleski J, Chan T, Weiss JM, Back TC, Yanaga K, Hanna N, Alexander HR, Maitra A, Hussain SP: Macrophage Migration Inhibitory Factor (MIF) induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma. Int. J. Cancer, July 23, Epub 2012.

 

 

 

 

Sohn JJ, Schetter AJ, Yfantis HG, Ridnour LA, Horikawa I, Khan MA, Robles AI, Hussain SP, Goto A, Bowman ED, Hofseth LJ, Bartkova J, Bartek J, Wogan GN, Wink DA, Harris CC: Macrophages, Nitric Oxide and microRNAs Are Associated with DNA Damage Response Pathway and Senescence in Inflammatory Bowel Disease. PLoS One, Sep 6, Epub 2012.