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Application Catalog

Program Description

NCI—FDA Joint Training in Cancer Prevention

Cancer Prevention Fellows are eligible to participate in the NCI—FDA joint training in cancer prevention initiative. This component of the CPFP provides training in cancer prevention and in the development and approval processes of drugs, biologic agents, devices, or nutritional products. The program's interdisciplinary training will enable scientists to more rapidly move novel chemopreventive agents and early detection methods from the laboratory to the community.

Background and Rationale. In 2003, the NCI Director and the FDA Commissioner joined forces to more rapidly identify effective cancer preventive agents and cancer treatments, thereby accelerating the process of introducing new agents into the clinic. Arising from this joint commitment was an initiative to train postdoctoral scientists and clinicians in research in cancer prevention, drug development, and regulatory review. Research training opportunities exist in several centers at the FDA in the areas of biologics (Center for Biologics Evaluation and Research (CBER)), drugs (Center for Drug Evaluation and Research (CDER)), medical devices and imaging (Center for Devices and Radiologic Health (CDRH)), and nutrition science and policy (Center for Food Safety and Nutrition (CFSAN)).

The NCI—FDA joint training in cancer prevention initiative will provide the opportunity for fellows to participate in all the activities of the CPFP at the NCI and in research and product development and regulatory review at the FDA. Combining training in public health, cancer prevention, and product development and regulatory research will allow individuals to develop expertise across three disciplines. This offers the possibility of developing novel agents and products, designing and implementing clinical trials in chemoprevention and early detection, and advancing the nutritional sciences.

Research Opportunities. General categories of research topics include:

  • Cancer risk of drug, device, and gene therapy products
  • Cellular substrates in vaccine development
  • Clinical trial design and analytic methodology
  • Development and selection of biomarkers and clinical endpoints in clinical trials
  • Development of chemopreventive agents
  • Genetic toxicology and cancer prevention
  • Genomic and proteomic approaches to early detection of cancer
  • Molecular and genetic approaches in product development
  • Nutrition science and policy
  • Screening and early detection
  • Vaccination and cancer prevention

Further information is available at

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