Specialized Programs of
Research Excellence
SPOREs


In 1992, the NCI established the Specialized Programs of Research Excellence (SPOREs) to promote interdisciplinary research and to speed the bidirectional exchange between basic and clinical science in order to move basic research findings from the laboratory to applied settings involving patients and populations. The ultimate goal of the SPORE program is to bring novel ideas that have the potential to reduce cancer incidence and mortality, improve survival, and to improve the quality of life to clinical care settings.

Laboratory and clinical scientists work collaboratively to plan, design and implement research programs that impact on cancer prevention, detection, diagnosis, treatment and control. To facilitate this research, each SPORE develops and maintains specialized resources that benefit all scientists working on the specific cancer site, as well as SPORE scientists. An additional SPORE element is a career development program that recruits scientists both within and outside the SPORE institution to enlarge the cadre of laboratory and clinical scientists dedicated to translational research on human cancer. SPOREs meet annually to share data, assess research progress, identify new research opportunities and establish priorities for research most likely to reduce incidence and mortality and to increase survival.

In 1996, NCI funded a total of 12 SPOREs and co-funded 6 SPORES for a total of $24,651,000. SPOREs are funded through specialized center grants, P50s. Twelve institutions received full support as P50 SPOREs. NCI co-funded three P50s from the National Institute of Diabetes and Digestive and Kidney Diseases using $501,000 of NCI support, and three P50s from the National Institute of Dental Research were co-funded using $1,042,000 of NCI support. In the upcoming years, NCI may increase the use of the SPORE mechanism to include funding for other major cancer sites.

Site Type Number of Awards Amount of Funding
Breast P50 6 $12,028,000
  Total Breast 6 12,028,000
Gastrointestinal P50 1 1,611,000
  Total Gastrointestinal 1 1,611,000
Lung P50 3 4,587,000
  Total Lung 2 4,587,000
Prostate P50 3 4,882,000
  Total Prostate 3 4,882,000
NIDDK P50 3 501,000
NIDR P50 3 1,042,000
  Total Co-funds 6 1,543,000
  Total SPORES   $24,651,000

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