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SUMMARY OF ACTION ITEMS - DEFINING NCI's ROLE

Three subcommittees were formed to carry out various action items:

1. Standard Reagents Subcommittee: Drs. Strausberg (contact), Brown, M. Showe, Staudt, and Weinstein. This group will give recommendations to NCI about what cell lines and RNAs should be used as controls, and determine the mechanism for their production and distribution. Sue Waldrop's office will set up an Internet site for communication with other workshop attendees. In the future, this group might consider, defining and distributing oligos for use in microarrays.
2. Informatics Subcommittee: Drs. Buetow (contact), Eisen, Friend, Masys and Rifkin. This group will develop a website for the sharing and distribution of protocols and software (immediate goal), and establish a data repository. The group will also work on data format issues, defining XML specifications, and communicating these specifications to other groups working on Gene Expression Markup Languages.
3. Gene Expression Analysis Workshop Subcommittee: Drs. Simon (contact), Kardia, Lander, Staudt, Tibshrani, and Willey. Additional volunteers: Drs. Brown, Eisen, Liu, Poggio, Taylor, and Weinstein. This group is charged with writing two review articles, addressing unresolved issues with respect to experimental platforms and analytic methods. The group is to use these reviews to inform the selection of problem sets which will be distributed to participants associated with the Director's Challenge for analysis, and then discussed at the Gene Expression Analysis Workshop, tentatively scheduled for winter 2001.

Useful websites mentioned or discussed

Molecular Pattern Recognition Whitehead/MIT Center for Genome Research

Data sets, Software, Protocols

http://www.genome.wi.mit.edu/MPR

AMAD (Another MicroArray Database)

Software, Technology, Protocols

http://www.microarrays.org

Gene Expression Markup Language (GEML) Rosetta Inpharmatics

http://www.rii.com/geml

The Brown Lab, Stanford University, Department of Biochemistry

The MGuide, Data sets

http://cmgm.stanford.edu/pbrown/

Cancer Genetics Branch National Human Genome Research Institute

Microarray project, protocols, image analysis, database design

http://www.nhgri.nih.gov/Intramural_research/Lab_cancer/

Incyte Genomics

http://www.incyte.com

Affymetrix

http://www.affymetrix.com

Array XML Working Group

Exchanging/ Storing Microarray Data

http://beamish.lbl.gov

Gene Expression Links

Large Scale Gene Expression and Microarrays Links and Resources

http://industry.ebi.ac.uk/~alan/MicroArray/

GRID IT

Resources for Microarray Technology

http://www.bsi.vt.edu/ralscher/gridit/

NIEHS Microarray Center

Methods, Bioinformatics, Chips

http://dir.niehs.nih.gov/microarray/

The Genomics and Bioinformatics Group, NCI

Data sets, protocols, software for data analysis and visualization

http://discover.nci.nih.gov

Contents page | Session I | Session II | Session III | Summary